Indication and Limitations of use

IMLYGIC® (talimogene laherparepvec) is a prescription medication injected on the skin, beneath the skin, or in your lymph glands to treat a type of skin cancer called melanoma when it can no longer be surgically removed. IMLYGIC® may not help you live longer and may not shrink cancer in your organs (for example, lung or liver).

RESOURCES AND SUPPORT

Introducing Support, Simplified

IMLYGIC® Resources and Support
Learn about IMLYGIC® Co-pay and Reimbursement Resources

LEARN ABOUT IMLYGIC® CO-PAY AND
REIMBURSEMENT RESOURCES

Amgen believes in the importance of helping patients get access to their prescribed medicine. If you have concerns about affording IMLYGIC® (talimogene laherparepvec), Amgen may be able to help.

IMLYGIC® FIRST STEP™ Program

IMLYGIC FIRST STEP™ Program

The IMLYGIC FIRST STEP™ Program can help eligible commercially insured patients reduce their out-of-pocket costs for IMLYGIC®.

  • For eligible commercially insured patients only
  • No out-of-pocket cost for the first dose or cycle, and $25 out-of-pocket cost for subsequent dose or cycle
  • Maximum benefit of $10,000 per calendar year
  • No income eligibility requirement
Qualifying for the IMLYGIC® FIRST STEP™ Program

Here’s what you need to qualify for IMLYGIC FIRST STEP™*:

  • Must be prescribed IMLYGIC®
  • Must have private commercial health insurance that covers medication costs for IMLYGIC®
  • Must not be a participant in any federal-, state-, or government-funded healthcare program such as Medicare, Medicare Advantage, Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), the Department of Defense (DoD), or TRICARE
  • May not seek reimbursement for value received from the IMLYGIC FIRST STEP™ Program from any third-party payers, including flexible spending accounts or healthcare savings accounts. If at any time patients begin receiving coverage under any federal-, state-, or government-funded healthcare program, patients will no longer be eligible to participate in the IMLYGIC FIRST STEP™ Program and must call 1‑888‑65‑STEP1 (1‑888‑657‑8371) Monday through Friday, 9 am–8 pm ET to stop participation. This is not health insurance. Program invalid where otherwise prohibited by law.
IMLYGIC® FIRST STEP™ Program Coverage Limits

Coverage limits:

  • Program covers out-of-pocket medication costs for IMLYGIC® only. Program does not cover any other costs related to office visit or administration of IMLYGIC®
  • No out-of-pocket cost for first dose or cycle; $25 out-of-pocket cost for subsequent dose or cycle; maximum benefit of $10,000 per patient per calendar year. Patient is responsible for costs above these amounts
  • Ongoing activation of the IMLYGIC FIRST STEP™ card is contingent on the submission of the required Explanation of Benefits (EOB) form by your healthcare provider’s office within 45 days of use of the IMLYGIC FIRST STEP™ card. Patients will be responsible for reimbursing the program for all amounts paid out if the EOB for the date of service is not received within 45 days

*Other restrictions apply. Not valid where prohibited by law. Amgen reserves the right to revise or terminate this program, in whole or in part, without notice at any time.


Get more program details here,
or call 1-888-65-STEP1 (1-888-657-8371).


Amgen Assist 360™

Amgen Assist 360™

We're Here for You

Discover how Amgen Assist 360™ can help refer you to resources most important to you.

Amgen Assist 360™ Nurse Ambassadors

Amgen Assist 360™ Nurse Ambassadors
Amgen Nurse Ambassadors are a single point of contact who takes the time to help you and your caregiver identify which types of assistance are most important to you. They will assist you in finding resources, so that you and your caregiver can focus on your treatment. They do not, however, provide medical advice or case management services*

Co-pay and Reimbursement Resources

Co-pay and Reimbursement Resources
Whatever insurance you have—even if you have none—the Nurse Ambassador can help you understand how your Amgen medicine may be covered and refer you to programs that may be able to help you afford it, such as IMLYGIC FIRST STEP™ or other independent nonprofit organizations

Transportation and Lodging

Help Finding Transportation and Lodging†
If you need assistance with travel that’s connected to your therapy, the Nurse Ambassador can put you in touch with independent nonprofit organizations that may provide you help with gas, tolls, parking, airfare, and lodging

Connections to Resources

Connections to Resources for Day-to-Day Living†
Sometimes you need someone who knows what you’re going through. The Nurse Ambassador can refer you to independent nonprofit organizations that may provide you with community resources,
one-on-one counseling services, and local support groups

Medication Answers

Medication Answers
If you have any questions about your Amgen medicine, the Nurse Ambassador may help you find the answers

*Patients should always talk to their healthcare provider about any medical decisions or concerns they may have.

†Resources include referrals to independent nonprofit patient assistance programs. Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofits' criteria. Amgen has no control over these programs and provides referrals as a courtesy only.


Call 888-4ASSIST (888-427-7478), Monday to Friday,
9 am to 8 pm ET or you can enroll here.


Finding a support network

Fighting melanoma can be a challenge. It is important to have a support network to rely
on during this difficult time. There are many options—here are a few that may help.

AIM At Melanoma Foundation

The AIM at Melanoma Foundation is an organization that provides information, support, educational symposia, and more for melanoma patients and their caregivers.1

Melanoma International Foundation

The Melanoma International Foundation offers guidance to melanoma patients and their loved ones with services that include patient outreach/support via email, a helpline, and an online forum.2

Melanoma Research Alliance

The Melanoma Research Alliance (MRA) funds research projects with the goal of making advances in the prevention, diagnosis, and treatment of melanoma. MRA partners with individuals, private foundations, and corporations on various initiatives, including public awareness campaigns.3

Melanoma Research Foundation

Visitors to the Melanoma Research Foundation website will find resources and tools for melanoma patients, including a treatment center finder, a Phone Buddy Program, an Ask a Nurse email program, and an online patient community.4

These resources are provided for your information. Amgen does not endorse or control the content of the third-party patient support sites listed above.

Patient And Care Partner Resources

IMLYGIC® Patient Brochure
Learn all you can about melanoma
and IMLYGIC®.

IMPORTANT SAFETY INFORMATION

Indication and Limitations of Use

What is IMLYGIC® used for? IMLYGIC® (talimogene laherparepvec) is a prescription medication used to treat a type of skin cancer called melanoma when it is on your skin or in your lymph glands. IMLYGIC® may not help you live longer and may not shrink cancer in your organs (for example, lung or liver).

IMPORTANT SAFETY INFORMATION

What is IMLYGIC® used for?

IMLYGIC® (talimogene laherparepvec) is a prescription medication used to treat a type of skin cancer called melanoma when it is on your skin or in your lymph glands.

IMLYGIC® may not help you live longer and may not shrink cancer in your organs (for example, lung or liver).

What is IMLYGIC® made from and how is it given?

  • IMLYGIC® is a weakened form of Herpes Simplex Virus Type 1, which is commonly called the cold sore virus. Your doctor will inject IMLYGIC® directly into your tumor(s).
  • Your doctor will decide which tumor(s) to inject and may not inject every one. It is important to care for the treatment sites properly so that IMLYGIC® does not spread to other people. Your doctor will show you how to do this.

Who should not take IMLYGIC®?

You should not get IMLYGIC® if you are pregnant or have a weakened immune system (for example, an immune deficiency, blood or bone marrow cancer, steroid use, or HIV/AIDS).

What should you tell your doctor before getting IMLYGIC®?

  • Because certain medications can affect your immune system, or affect how IMLYGIC® works, tell your doctor if you are taking steroids or other medicines that suppress your immune system, or are taking antiviral medications to treat or prevent herpes, like acyclovir.
  • Tell your doctor if you have or ever had certain medical conditions like: HIV infection or AIDS, blood or bone marrow cancer, autoimmune disease, or other medical conditions that can weaken your immune system.
  • Tell your doctor if you have close contact with someone who has a weakened immune system or is pregnant.
  • IMLYGIC® may harm your unborn baby. Tell your doctor if you are pregnant or planning to become pregnant, nursing, or planning to breastfeed. You should not become pregnant during treatment with IMLYGIC®. Your doctor will determine whether you should receive IMLYGIC®. Talk to your doctor about effective birth control methods.
  • Tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IMLYGIC® may affect the way other medicines work and other medicines may affect how IMLYGIC® works.

The IMLYGIC® virus can spread to other areas of your body or to your close contacts (household members, caregivers, sex partners, or persons sharing the same bed). Do the following to avoid spreading IMLYGIC® to other areas of your body or to your close contacts. You should share this information with them:

  • Avoid direct contact between your treatment sites, dressings, or body fluids and close contacts (for example, use condoms when engaging in sexual activity, avoid kissing close contacts if either of you has an open mouth sore).
  • Don’t touch or scratch the parts of your body that have been injected with IMLYGIC®.
  • Wear gloves while putting on or changing your dressings.
  • Keep treatment sites covered with airtight and watertight dressings for at least 1 week after each treatment (or longer if the treatment site is weeping or oozing).
  • Replace dressings right away with a clean dressing if they become loose or come off.
  • Place all used dressings and cleaning materials in a sealed plastic bag, and throw them away in the garbage.

What are the possible side effects of IMLYGIC®?

  • Common side effects of IMLYGIC® include tiredness, chills, fever, nausea, flu-like symptoms, and pain at treatment site.
  • Tell your doctor right away if you get any of the following:
  • Pain, burning, or tingling in a blister around the mouth or genitals or on the fingers or ears
  • Eye pain, light sensitivity, discharge from the eyes, or blurry vision
  • Weakness in arms or legs
  • Extreme drowsiness (feeling sleepy)
  • Mental confusion
  • If you think you have a herpes infection, inform your doctor. You or your doctor should call Amgen at
    1-855-IMLYGIC (1-855-465-9442) for follow-up testing, if needed.
  • Tell your doctor if you have any side effect that bothers you or does not go away.
  • These are not all the possible side effects of IMLYGIC®.

If you would like more information, talk with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or
call 1-800-FDA-1088.

Please see full Prescribing Information and Medication Guide for more information about IMLYGIC®.

Indication and Limitations of Use

IMLYGIC® (talimogene laherparepvec) is a prescription medication injected on the skin, beneath the skin, or in your lymph glands, to treat a type of skin cancer called melanoma when it can no longer be surgically removed.

IMLYGIC® may not help you live longer and may not shrink cancer in your organs (for example, lung or liver).

References:

1. AIM at Melanoma. AIM mission. http://www.aimatmelanoma.org/aim-mission. Accessed May 2, 2018.
2. Melanoma International Foundation. Programs & services. http://melanomainternational.org/who-we-are/programs/#.Veo55f9Lhdg. Accessed May 2, 2018.
3. Melanoma Research Alliance. http://www.curemelanoma.org. Accessed May 2, 2018.
4. Melanoma Research Foundation. http://www.melanoma.org. Accessed May 2, 2018.